Correlation between echo morphological carotid plaque characteristics and neurological symptoms

The correlation of carotid plaque pathohistologic features and neurological symptoms: a meta-analysis of observational studies.

OBJECTIVE To investigate the association between the pathological features of carotid plaque and ipsilateral symptoms of cerebral ischemia. MATERIALS AND METHODS We sought to identify clinical observational studies comparing the incidence of pathological features between symptomatic and asymptomatic carotid plaques in terms of ulceration, thrombosis and intraplaque hemorrhage (IPH), published...

Ultrasonographic assessment of the morphological characteristics of the carotid plaque.

Apart from the degree of stenosis, plaque morphology has emerged in recent years as an important contributory factor in stroke risk. Ultrasound studies have shown that hypo- or anechogenic plaques carry a higher risk of cerebrovascular events than echogenic ones. Similarly, heterogeneous plaques presenting a complex pattern of echogenicity in ultrasound have also been more frequently associated...

Carotid Plaque Morphology: Plaque Instability and Correlation with Development of Ischaemic Neurological Events

Invited commentary. The correlation of carotid plaque pathohistological features and neurological symptoms: a meta-analysis of observational studies.

The authors have carried out an important service by their meta-analysis, which strengthens the evidence that plaque characteristics are strongly associated with clinical outcomes. They have shown clearly that ulceration is a feature of plaques that are vulnerable to rupture; intraplaque hemorrhage is also associated with events in their linear analysis. In the search for identifying patients w...

Carotid Plaque Morphology Is Significantly Associated With Sex, Age, and History of Neurological Symptoms.

BACKGROUND AND PURPOSE The purpose of this study was to analyze the association between morphological characteristics of human carotid plaques and patient's sex, age, and history of neurological symptoms. METHODS The study included 763 atherosclerotic plaques from patients treated surgically for carotid stenosis between 2004 and 2013. Histological analyses of carotid plaques were performed to...